Peer-reviewed veterinary case report
Dog had seizures and high fever after wrong spinal contrast injection
By Roux, Françoise A & Deschamps, Jack-Yves·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2007·Nantes School of Veterinary Medicine, France·View original on PubMed →
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Original publication title: Inadvertent intrathecal administration of ionic contrast medium to a dog.
- Species:
- dog
Plain-English summary
A dog experienced severe seizures and muscle spasms after a hyperosmolar ionic contrast medium was mistakenly injected into its spine during a procedure called myelography. This led to symptoms like uncontrollable shaking and a high fever, known as "ascending tonic-clonic seizure syndrome." Fortunately, the dog fully recovered within 24 hours after the incident. This case highlights the importance of using only safe, nonionic contrast media for such procedures to avoid serious complications.
People also search for: dog seizures after myelography · dog shaking uncontrollably · what to do if my dog has a seizure
Abstract
A hyperosmolar ionic contrast medium, ioxithalamate (Telebrix), was inadvertently injected intrathecally to a dog during myelography. The resultant severe adverse effects were myoclonus, uncontrollable seizures, and hyperthermia. These symptoms have been described by some authors as "ascending tonic-clonic seizure syndrome". The dog completely recovered within 24 h. The literature on 47 humans receiving intrathecal ionic contrast medium after 1966, one dog and one horse was reviewed, including the drugs involved, the circumstances of their use, and the symptoms, treatment and outcome of patients who received the drugs intrathecally. Recommendations to prevent such a misuse are given. The present report and review are a reminder that ionic contrast media are absolutely contraindicated for myelography. Only nonionic contrast media can be used intrathecally. All of the hyperosmolar contrast media are ionic and therefore contraindicated for myelography.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17899973/