Peer-reviewed veterinary case report
IncFII Conjugative Plasmid-Mediated Transmission of blaNDM-1 Elements among Animal-Borne Escherichia coli Strains.
- Journal:
- Antimicrobial agents and chemotherapy
- Year:
- 2017
- Authors:
- Lin, Dachuan et al.
- Affiliation:
- Hong Kong PolyU Shen Zhen Research Institute · China
Abstract
This study aims to investigate the prevalence and transmission dynamics of the blagene in animal Escherichia coli strains. Two IncFII bla-encoding plasmids with only minor structural variation in the MDR region, pHNEC46-NDM and pHNEC55-NDM, were found to be responsible for the transmission of blain these strains. The blagene can be incorporated into plasmids and stably inherited in animal-borne E. coli strains that can be maintained in animal gut microflora even without carbapenem selection pressure.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/27821455/