Peer-reviewed veterinary case report
Bacteremia risk after stomach biopsy in healthy dogs with omeprazole
By Jones, Katherine R et al.·Published in American journal of veterinary research·2013·Department of Veterinary Clinical Medicine, United States·View original on PubMed →
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Original publication title: Incidence of bacteremia following upper gastrointestinal endoscopy and biopsy in healthy dogs before, during, and after treatment with omeprazole.
- Species:
- dog
Plain-English summary
Eight healthy dogs underwent a procedure called endoscopy to examine their stomachs and take biopsies. Researchers wanted to see if this procedure caused any bacteria to enter the bloodstream and if a medication called omeprazole, used to reduce stomach acid, had any effect on this. After testing blood samples, they found that only two dogs showed signs of bacteria at different times, while most dogs had no issues. Overall, the endoscopy didn't lead to detectable bacteria in the blood, and omeprazole didn't change this outcome.
People also search for: dog endoscopy risks · omeprazole for dogs · dog stomach biopsy recovery
Abstract
OBJECTIVE: To determine the incidence of bacteremia, as detected by routine methods for bacterial culture of blood samples, following routine endoscopic biopsy of the stomach and duodenum in healthy research dogs and to determine whether treatment with omeprazole administration affected the incidence of bacteremia. ANIMALS: 8 healthy purpose-bred research dogs. PROCEDURES: All dogs underwent gastroduodenoscopy with biopsy at 4 points: twice prior to treatment with omeprazole, once following 15 days of omeprazole treatment (20 mg, PO, q 12 h), and once 14 days after treatment ceased. Dogs had a mean ± SD body weight of 18.6 ± 2.0 kg. Blood samples were aseptically obtained at 3 points during each procedure (before, immediately following, and 24 hours after endoscopy), and routine aerobic and anaerobic bacterial culture of blood was performed. RESULTS: 96 cultures were attempted for each culture method, yielding positive results of aerobic culture for 2 dogs at separate time points and no positive results of anaerobic culture. CONCLUSIONS AND CLINICAL RELEVANCE: Routine gastrointestinal endoscopy with biopsy in healthy dogs did not result in a detectable bacteremia in most dogs. Treatment with the gastric acid-suppressing medication omeprazole did not affect the incidence of bacteremia as detected via standard techniques.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23363348/