Peer-reviewed veterinary case report
Incidence of Trypanosoma cruzi transmission through breastfeeding during acute experimental Chagas disease.
- Journal:
- The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
- Year:
- 2011
- Authors:
- Martins, Luciamare Perinetti Alves et al.
- Affiliation:
- Faculdade de Medicina de Marí · Brazil
- Species:
- rodent
Abstract
OBJECTIVE: To verify the incidence of T. cruzi transmission through breastfeeding during acute experimental Chagas' disease. METHODS: Fifteen female Swiss mice were mated and, after pregnancy confirmation, placed in individual cages. A few hours after birth, the females were inoculated with 0.1 mL of blood containing approximately 3 x 10(5) trypomastigote forms of Y strain of T. cruzi and continued breastfeeding for 25 days. RESULTS: In 142 offspring examined no infection through breast-feeding was observed. CONCLUSIONS: The low number of trypomastigote forms ingested by the newborn mice combined with biological and biochemical characteristics of blood trypomastigotes may explain the lack of transmission in this experiment.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/21503396/