Peer-reviewed veterinary case report
Signs and kidney injury after grape or raisin eating in dogs and cats
By Dijkman, M A et al.·Published in The Journal of small animal practice·2022·University Medical Center Utrecht, Netherlands·View original on PubMed →
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Original publication title: Incidence of Vitis fruit-induced clinical signs and acute kidney injury in dogs and cats.
Plain-English summary
A group of 95 dogs and 13 cats were studied after eating grapes or raisins (Vitis fruit), which can be harmful. About 15% of these pets showed symptoms like vomiting, lethargy, diarrhea, and loss of appetite, but only one dog developed serious kidney injury. Veterinarians often induced vomiting to remove the fruit, which was effective, especially if done within 12 hours of ingestion. Most pets recovered well after treatment, highlighting the importance of acting quickly if your pet eats grapes or raisins.
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Abstract
OBJECTIVES: To determine the incidence of clinical signs and Vitis fruit-induced acute kidney injury in dogs and cats with a Vitis fruit ingestion reported to the Dutch Poisons Information Center, and a description of the therapies instituted by the veterinarians. MATERIALS AND METHODS: All cases of Vitis fruit ingestions in dogs and cats reported to the center between January 1, 2018 and December 31, 2018 were included in this study. Veterinarians and pet owners were contacted by phone or email to obtain follow-up information. Information was collected using a standardised data collection sheet. RESULTS: Ninety-five dogs and 13 cats with proven Vitis fruit ingestion were included. Fourteen dogs and two cats developed clinical signs: emesis (11/16, 68.8%), lethargy (5/16, 31.3%), diarrhoea (3/16, 18.8%), anorexia (3/16, 18.8%), tremor (2/16, 12.5%) and restlessness (1/16, 6.3%). The overall incidence for developing clinical signs was 14.7% in dogs and 15.4% in cats. One (1/95, 1%) dog developed acute kidney injury after ingestion of Vitis fruit. No cats developed acute kidney injury. Induction of emesis and/or administration of activated charcoal was instituted in 72 of 82 (88%) and eight of 11 (73%) of asymptomatic dogs and cats and six of 14 (43%) and two of two (100%) of symptomatic dogs and cats, respectively. Overall, emesis was induced in 72 of 95 (76%) dogs (100% success rate) and removed Vitis fruits in the majority of cases (98% when induced <4 hours after ingestion and 83% when induced 4 to 12 hours after ingestion). Emesis was induced in seven of 13 (54%) cats (86% success rate) and removed Vitis fruits in 83% of the cases. CLINICAL SIGNIFICANCE: In this study, a significant proportion (around 15%) of dogs and cats developed clinical signs after ingestion of Vitis fruits, which were predominantly related to the gastrointestinal tract. Symptomatic acute kidney injury was rare. Our findings suggest the use of decontamination measures, i.e. induction of emesis, may be warranted up to 12 hours after ingestion.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35137417/