Peer-reviewed veterinary case report
Incidental mononuclear cell infiltrate in the uvea of cynomolgus monkeys.
- Journal:
- Toxicologic pathology
- Year:
- 2006
- Authors:
- Sinha, Dinesh P et al.
- Affiliation:
- Department of Drug Safety and Metabolism · United States
Abstract
Mononuclear cell infiltrate (MCI) in the uvea was observed in naïve, untreated (control group) cynomolgus monkeys in approximately 25% of drug safety evaluation studies. The total incidence of MCI in the choroid and the ciliary body was 29% of 342 males and 25% of 306 female monkeys. In the studies in which MCI was present in the ciliary body or choroid, the incidence was as high as 75%. There were no other ocular histopathologic findings in these monkeys. All monkeys were clinically healthy and the eyes were not remarkable when examined ophthalmoscopically.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16537293/