Peer-reviewed veterinary case report
Increased formation of autophagosomes in ectromelia virus-infected primary culture of murine bone marrow-derived macrophages.
- Journal:
- Acta virologica
- Year:
- 2013
- Authors:
- Martyniszyn, L et al.
Abstract
Induction of autophagy by ectromelia virus (ECTV) in primary cultures of bone marrow-derived macrophages (BMDMs) was investigated. The results showed that ECTV infection of BMDMs resulted in increased formation of autophagosomes, increased level of LC3-II protein present in aggregates and extensive cytoplasmic vacuolization. These data indicate an increased autophagic activity in BMDMs during ECTV infection.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/24294965/