Peer-reviewed veterinary case report
Older dogs and low blood pressure during surgery linked to death
By Ullal, Tarini V et al.·Published in Journal of the American Veterinary Medical Association·2023·School of Veterinary Medicine, United States·View original on PubMed →
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Original publication title: Increasing age and severe intraoperative hypotension associated with nonsurvival in dogs with gallbladder mucocele undergoing cholecystectomy.
- Species:
- dog
Plain-English summary
A group of 25 dogs with gallbladder mucoceles (a condition where the gallbladder is filled with mucus) underwent surgery to remove the gallbladder. Unfortunately, older dogs and those that experienced low blood pressure during surgery had a higher chance of not surviving the procedure or the immediate recovery period. Overall, 76% of the dogs survived to leave the hospital, and 68% were still alive two weeks later. The study found that while certain inflammatory markers were higher in dogs with this condition, they did not predict survival outcomes after surgery.
People also search for: dog gallbladder mucocele surgery survival rate · older dog surgery risks · low blood pressure in dogs during surgery
Abstract
OBJECTIVE: To identify prognostic indicators and inflammatory markers associated with nonsurvival in dogs with gallbladder mucoceles (GBMs) following cholecystectomy and to evaluate C-reactive protein (CRP) and haptoglobin concentrations in dogs with GBMs compared to healthy controls. ANIMALS: 25 dogs that underwent cholecystectomy for removal of GBM and 20 healthy control dogs. METHODS: A prospective, multicenter cohort study. Survival outcomes to hospital discharge and 2 weeks postdischarge were recorded from medical records. Laboratory variables, inflammatory markers (CRP and haptoglobin), and 25-hydroxyvitamin(OH) D (25[OH]D) concentrations were measured preoperatively. Associations between signalment, clinicopathologic variables, acute patient physiologic and laboratory evaluation (APPLEFAST) scores, inflammatory markers, 25(OH)D concentration, and survival were analyzed using logistic regression. RESULTS: 76% (19/25) and 68% (17/25) of dogs survived to hospital discharge and 2 weeks postdischarge, respectively. For each additional year of age, the odds of nonsurvival in hospital and 2 weeks postdischarge increased by 2.2 (P = .01; 95% CI, 1.2 to 5.0) and 1.7 (P = .04; 95% CI, 1.0 to 3.2), respectively. Intraoperative systolic blood pressure ≤ 65 mm Hg increased the probability of nonsurvival in hospital (P < .04). Gallbladder perforation, APPLEFAST scores, and preoperative serum concentrations of CRP, haptoglobin, and 25(OH)D were not associated with survival. Serum CRP and haptoglobin concentrations were greater in dogs with GBM compared to controls (P < .001). CLINICAL RELEVANCE: Increasing age and intraoperative systolic blood pressure ≤ 65 mm Hg were associated with nonsurvival in dogs with GBM undergoing cholecystectomy. Serum CRP, haptoglobin, and 25(OH)D were not associated with nonsurvival postcholecystectomy in this sample population.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37669748/