Peer-reviewed veterinary case report
Indirect activation of rhesus macaque (Macaca mulatta) NK cells in oral and mucosal draining lymph nodes.
- Journal:
- Journal of medical primatology
- Year:
- 2018
- Authors:
- Ram, Daniel R et al.
- Affiliation:
- Harvard Medical School · United States
Abstract
The oral mucosae and draining lymph nodes are primary entry points for invading pathogens, particularly during immunosuppressive HIV/SIV infections. Innate immunity against oral stimuli, including natural killer (NK) cells, is understudied. Herein, we demonstrate functional NK cell responses to pathogen-associated molecular patterns (PAMPs) of potential oral pathogens in rhesus macaques.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/30256418/