Peer-reviewed veterinary case report
Induced murine models of systemic lupus erythematosus.
- Journal:
- Methods in molecular biology (Clifton, N.J.)
- Year:
- 2014
- Authors:
- Xu, Yuan et al.
- Affiliation:
- Department of Medicine · United States
Abstract
Induced mouse models of systemic lupus erythematosus (SLE) have been developed to complement the spontaneous models. This chapter describes the methods used in the pristane-induced model and the chronic graft-versus-host disease (cGVHD) model, both of which have been extensively used. We will also outline the specific mechanisms of systemic autoimmunity that can be best characterized using each of these models.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/24497358/