Peer-reviewed veterinary case report
Inducible ablation of CD11ccells to determine their role in skin wound repair.
- Journal:
- Immunology
- Year:
- 2021
- Authors:
- Li, Zhi et al.
- Affiliation:
- Department of Biosciences · United Kingdom
Abstract
Whether resident and recruited myeloid cells may impair or aid healing of acute skin wounds remains a debated question. To begin to address this, we examined the importance of CD11c+ myeloid cells in the early activation of skin wound repair. We find that an absence of CD11c+ cells delays wound closure and epidermal proliferation, likely due to defects in the activation of the IL-23-IL-22 axis that is required for wound healing.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/33502012/