Peer-reviewed veterinary case report
Induction of SAP7 correlates with virulence in an intravenous infection model of candidiasis but not in a vaginal infection model in mice.
- Journal:
- Infection and immunity
- Year:
- 2005
- Authors:
- Taylor, Brad N et al.
- Affiliation:
- Institute of Clinical Microbiology · Germany
- Species:
- rodent
Abstract
SAP7 of Candida albicans is induced after vaginal infection of mice. Conversely, virulence during vaginal infection was not affected in a Deltasap7/Deltasap7 mutant strain. Only a partial virulence phenotype was detectable after intravenous injection. In conclusion, SAP7 expression does not correlate with C. albicans virulence in mice.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16177393/