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Peer-reviewed veterinary case report

Infection by the Sylvio X10/4 clone of Trypanosoma cruzi: relevance of a low-virulence model of Chagas' disease.

Journal:
Microbes and infection
Year:
2009
Authors:
Marinho, Cláudio R F et al.
Affiliation:
Department of Immunology · Brazil
Species:
rodent

Abstract

The physiopathology of Chagas' disease has been largely defined in murine infections with virulent strains which partially represent parasite diversity. This report reviews our studies with Sylvio X10/4 parasites, a Trypanosoma cruzi clone that induces no acute phase but in C3H/He mice leads to chronic myocarditis resembling the human disease.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/19660570/