Peer-reviewed veterinary case report
Infectivity of Cryptosporidium hominis and Cryptosporidium parvum genotype 2 isolates in immunosuppressed Mongolian gerbils.
- Journal:
- Infection and immunity
- Year:
- 2005
- Authors:
- Baishanbo, Asiya et al.
- Affiliation:
- Laboratoire d'Immunologie et d'Immunopathologie · France
- Species:
- rodent
Abstract
One-month-old dexamethasone-immunosuppressed Mongolian gerbils were challenged with 1 oocyst to 2 x 10(5) oocysts from two isolates genotyped as Cryptosporidium hominis and C. parvum (genotype 2), respectively. A similar dose-dependent gut infection was obtained, and the initial genotype maintained for 21 to 22 days. The data suggest that immunosuppressed gerbils provide a reliable rodent model of persistent C. hominis infection.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16041051/