Peer-reviewed veterinary case report
Blood and inflammation markers rise with parvovirus severity in dogs
By Kocaturk, M et al.·Published in The Journal of small animal practice·2015·Department of Internal Medicine·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Inflammatory and oxidative biomarkers of disease severity in dogs with parvoviral enteritis.
- Species:
- dog
Plain-English summary
A group of dogs with parvoviral enteritis, a serious viral infection that causes severe vomiting and diarrhea, showed significant changes in certain blood markers related to inflammation and oxidative stress. The study found that dogs with more severe symptoms had higher levels of C-reactive protein, which indicates inflammation, compared to healthier dogs. While all affected dogs had increased haptoglobin levels, this did not vary with the severity of their illness. These findings suggest that monitoring C-reactive protein levels could help veterinarians assess how severe a dog's parvoviral infection is and guide treatment decisions.
People also search for: dog parvovirus symptoms · how to treat parvoviral enteritis in dogs · dog vomiting and diarrhea treatment
Abstract
OBJECTIVES: To study changes in serum C-reactive protein, haptoglobin, ceruloplasmin and albumin concentration, total anti-oxidant capacity and paraoxonase-1 and butyrylcholinesterase activity in dogs with parvoviral enteritis of different degrees of clinical severity. METHODS: Prospective study of 9 healthy and 43 dogs with parvoviral enteritis that were classified into mildly, moderately and affected groups. RESULTS: Dogs with parvoviral enteritis had a significant increase in C-reactive protein compared with healthy dogs, with an increase of higher magnitude in animals with more severe clinical signs. All dogs with parvoviral enteritis had a significant increase in haptoglobin concentration compared with healthy dogs, but with no difference according to disease severity. There was a decrease in paraoxonase-1 activity in parvoviral enteritis. CLINICAL SIGNIFICANCE: Major increases of C-reactive protein concentrations in dogs with parvoviral enteritis are a marker of disease severity. In addition, higher values for anti-oxidants in severe cases compared with mild and moderate cases suggest a possible compensatory anti-oxidant mechanism.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25040669/