Peer-reviewed veterinary case report
Inflammatory tumor found in a dog's pancreas after death
By Romanucci, Mariarita et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2019·Faculty of Veterinary Medicine, Italy·View original on PubMed →
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Original publication title: Inflammatory myofibroblastic tumor of the pancreas in a dog.
- Species:
- dog
Plain-English summary
A 5-year-old male Rottweiler was found to have a large mass in the pancreas after he died from severe breathing problems, following a period of not eating and being unusually tired. The mass was made up of abnormal cells and showed signs of tissue damage. Unfortunately, the dog did not survive, and the tumor was identified as an inflammatory myofibroblastic tumor, which is a rare type of growth. This case highlights the importance of recognizing symptoms like lethargy and loss of appetite, which can indicate serious underlying issues.
People also search for: dog pancreatic tumor symptoms · Rottweiler breathing problems · dog lethargy and anorexia
Abstract
A large, ill-defined, firm, multinodular mass involving the pancreas was confirmed on postmortem examination of a 5-y-old, male Rottweiler that died following acute respiratory distress syndrome, after a period of anorexia and lethargy. Histologically, the mass consisted of plump spindle cells admixed with a variable number of macrophages, lymphocytes, plasma cells, and neutrophils. Foci of coagulative necrosis and hemorrhage were also observed. Spindle cells strongly reacted to antibodies against vimentin, α-smooth muscle actin, and calponin, whereas desmin was expressed only mildly and focally. Pan-cytokeratin, KIT, glial fibrillary acidic protein, and S100 protein were nonreactive. Variable numbers of MAC 387-positive cells, CD3+ lymphocytes, and numerous blood vessels were also detected throughout the mass. Histologic and IHC findings were consistent with a diagnosis of inflammatory myofibroblastic tumor of the pancreas.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31585512/