Peer-reviewed veterinary case report
Amino acid IV infusions raise albumin in dogs with low levels
By Schneider, Sabrina et al.·Published in Frontiers in veterinary science·2023·Clinic of Small Animal Medicine, Germany·View original on PubMed →
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Original publication title: Influence of intravenous 10% amino acids infusion on serum albumin concentration in hypoalbuminemic dogs.
- Species:
- dog
Plain-English summary
A group of dogs with low albumin levels (hypoalbuminemia) received an intravenous amino acid solution for several days while hospitalized. The treatment helped raise their albumin levels within two days, but it didn't change their overall survival rates or outcomes compared to dogs that didn't receive the amino acids. However, the dogs that got the amino acids stayed in the hospital longer. This suggests that while the amino acids can improve albumin levels, they may not affect how well the dogs ultimately do.
People also search for: dog low albumin treatment · hypoalbuminemia in dogs · intravenous amino acids for dogs
Abstract
OBJECTIVE: To evaluate the effect of parenteral amino acid application in hospitalized hypoalbuminemic dogs. MATERIALS AND METHODS: Medical records of client-owned hypoalbuminemic dogs (albumin ≤ 25 g/L) were analyzed. Dogs receiving amino acids for only 1-2 days, receiving transfusions or surgery, or <6 months of age were excluded. Dogs were grouped as those receiving intravenous amino acids (AA, 80 dogs) over 3 days and longer, and those without additional amino acid treatment (CON, 78 dogs). Duration of hospitalization, albumin, and total protein concentrations were compared between groups by Mann-Whitney U test. Course of albumin and total protein concentration was evaluated by Friedman test and Dunn's multiple comparison test. Significance was set to ≤ 0.05. RESULTS: Dogs in group AA received 10% amino acid solution intravenously over median 4 days (3-11 days). No significant differences regarding survival and adverse effects were observed between groups. Dogs of group AA had significantly longer duration of hospitalization (median 8 days; 3-33 days) compared to group CON dogs (median 6 days, 3-24 days; < 0.001). Initial albumin concentration was lower in group AA compared to CON ( < 0.001). This difference was no longer present on day 2 ( = 0.134). CONCLUSIONS AND CLINICAL RELEVANCE: Intravenous application of 10% amino acid solution in hypoalbuminemic dogs can improve albumin concentration after 2 days, but does not influence outcome.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37342623/