Peer-reviewed veterinary case report
Ingol and ingenol diterpenes from the aerial parts of Euphorbia royleana and their antiangiogenic activities.
- Journal:
- Journal of natural products
- Year:
- 2009
- Authors:
- Li, Xiao-Li et al.
- Affiliation:
- Kunming Institute of Botany · China
Abstract
Ten new ingol lathyrane-type diterpenes (1-10) and two known ingenol derivatives (11 and 12) were isolated from the aerial parts of Euphorbia royleana. The structures of 1-10 were elucidated on the basis of spectroscopic methods including 2D NMR analysis, and the structure of compound 1 was confirmed by single-crystal X-ray crystallography. Antiangiogenic effects of all compounds except for 5 were tested using a zebrafish model, with compounds 11 and 12 being active in this bioassay.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/19438253/