Peer-reviewed veterinary case report
Progressive muscle weakness from inherited myopathy in a young Great
By McMillan, Chantal J et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2006·Western College of Veterinary Medicine, Canada·View original on PubMed →
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Original publication title: Inherited myopathy in a young Great Dane.
Plain-English summary
A 3-year-old male Great Dane was brought in due to 18 months of increasing weakness. Tests on muscle samples showed changes typical of a condition known as central core myopathy, which is inherited in this breed. Unfortunately, this condition can lead to ongoing muscle issues, and while specific treatments weren't detailed, managing symptoms and supportive care are often recommended for dogs with inherited myopathies.
People also search for: Great Dane weakness · inherited myopathy in dogs · central core myopathy treatment
Abstract
A 3-year-old, male Great Dane was evaluated for an 18-month history of progressive weakness. Histologic evaluation of muscle biopsies revealed distinct cytoarchitectural changes that were indistinguishable from the central "core-like" structures previously described as central core myopathy in this breed. Clinical features of this inherited myopathy are described.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17017655/