Peer-reviewed veterinary case report
Inhibition of breast adenocarcinoma growth by intratumoral injection of lipophilic long-acting lathyrogens.
- Journal:
- Anti-cancer drugs
- Year:
- 2005
- Authors:
- Chvapil, Milos
- Affiliation:
- Arizona Cancer Center and Department of Surgery · United States
Abstract
Prevention of the formation of crosslinks and/or disintegration of already formed collagen fibrils in the tumor by known lathyrogens, beta-aminopropionitrile or D-penicillamine, may result in the weakening of tumor support, decreasing angiogenesis and promoting tumor regression. This paper reviews our studies with a single intratumoral injection of lipophilic lathyrogens and others, using a systemic administration to investigate the effect of both lathyrogens. Details of our experimental results are also given.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15655419/