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Peer-reviewed veterinary case report

Insulinoma diagnosed in normoglycemic golden retriever dog

By Mellanby, R J & Herrtage, M E·Published in The Journal of small animal practice·2002·Queen's Veterinary School Hospital, United Kingdom·View original on PubMed

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Original publication title: Insulinoma in a normoglycaemic dog with low serum fructosamine.

Species:
dog

Plain-English summary

An 8-year-old male golden retriever was diagnosed with insulinoma, a type of tumor that affects insulin production, despite having normal blood sugar levels during tests. Over seven weeks, the dog's blood sugar was consistently within the normal range, but tests showed low fructosamine levels, which can indicate issues with insulin regulation. After surgery to remove a nodule from the pancreas, the diagnosis was confirmed. This case highlights that dogs with insulinoma can still have normal blood sugar readings, and low fructosamine levels can be a useful indicator for vets when diagnosing this condition.

People also search for: dog insulinoma symptoms · golden retriever low blood sugar · insulinoma treatment for dogs

Abstract

An insulinoma was diagnosed in an eight-year-old, male golden retriever. Four fasted serum glucose concentrations were within the reference values over a seven-week period. Two serum fructosamine values over the same seven-week period were both low. An exploratory laparotomy and histopathology of an excised pancreatic nodule confirmed the diagnosis of insulinoma. This report demonstrates that a dog with a histologically confirmed insulinoma can have normal fasting serum glucose concentrations on multiple assays. It also demonstrates that fructosamine assays may be helpful in the diagnostic evaluation of normoglycaemic dogs with clinical signs suggestive of insulinoma.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12463268/