Peer-reviewed veterinary case report
Radiation and chemo outcomes for dogs with right atrial tumors
By Moirano, Steven et al.·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2023·Department of Surgical Sciences, United States·View original on PubMed →
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Original publication title: Intensity-modulated radiotherapy and chemotherapy for canine right atrial tumors: A retrospective study of seven dogs.
- Species:
- dog
Plain-English summary
A group of seven dogs with right atrial tumors, most commonly hemangiosarcoma, were treated with a combination of radiation therapy and chemotherapy. After treatment, one dog showed complete recovery, four had partial improvements, and two remained stable. All dogs had their fluid buildup resolved, and the average time before the disease worsened was about 290 days. While five dogs passed away due to cancer spread, one dog is still alive, and three dogs with hemangiosarcoma survived between 244 and 445 days. The treatment was generally well tolerated, suggesting it may help dogs with these types of tumors.
People also search for: dog heart tumor treatment · hemangiosarcoma in dogs prognosis · canine chemotherapy side effects
Abstract
Most primary cardiac tumors in dogs are located in the right atrium/atrial appendage, with hemangiosarcoma being the most common. The aims of this retrospective, case series were to describe outcomes for seven dogs with right atrial tumors treated with hypofractionated intensity-modulated radiotherapy and concurrent vinblastine and propranolol. One dog had a complete response, four dogs had partial responses and two dogs had stable disease after treatment. Effusions resolved in all dogs. Median progression-free survival was 290 days. Five dogs died from metastatic disease, one dog from unrelated neoplasia, and one dog is alive. Median overall survival was 326 days. Three dogs with confirmed hemangiosarcoma survived 244, 326, and 445 days. Two dogs developed clinically significant, but nonfatal, cardiac arrhythmias. One dog that received three courses of radiation had subclinical myocardial and arterial fibrosis at necropsy. Hypofractionated chemoradiotherapy was well tolerated and may provide clinical benefit in dogs with right atrial tumors.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37800663/