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Peer-reviewed veterinary case report

Intestinal Tyzzer's Disease and Spirochetosis in a Guinea Pig

Journal:
Veterinary Pathology
Year:
1977
Authors:
McLeod, C. G. et al.
Affiliation:
Pathology Division, U. S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Md.
Species:
rodent

Abstract

Tyzzer's disease (bacillus piliformis infection) was diagnosed in a young guinea pig killed because of diarrhea and poor condition. There was necrosis and inflammation of the colon, cecum and ileum. Typical B. piliformis were in intestinal epithelial cells. Spirochetes were in large numbers in intestinal crypts and were often adjacent to the intracellular B. piliformis. Extracellular B. piliformis occasionally were surrounded by spirochetes.

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Original publication: https://doi.org/10.1177/030098587701400305