Peer-reviewed veterinary case report
Dogs treated with cisplatin during surgery for limb soft tissue tumors
By Havlicek, M et al.·Published in Veterinary and comparative oncology·2009·Veterinary Specialist Centre, United Kingdom·View original on PubMed →
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Original publication title: Intra-operative cisplatin for the treatment of canine extremity soft tissue sarcomas.
- Species:
- dog
Plain-English summary
Nineteen dogs with soft tissue tumors on their legs were treated with surgery and a special chemotherapy called cisplatin, delivered through a biodegradable implant. Although most dogs experienced some wound complications after the procedure, nearly half were still alive more than two years later. However, some dogs did have their tumors come back after a certain time. This treatment showed promise, but pet owners should be aware of the potential for complications and recurrence.
People also search for: dog soft tissue sarcoma treatment · cisplatin for dog cancer · dog tumor surgery recovery
Abstract
Nineteen dogs with histologically confirmed soft tissue sarcomas of the extremities were treated with a combination of marginal surgery and intra-operative chemotherapy in the form of cisplatin in a biodegradable implant delivery system (Atrigel; Atrix Laboratories, Fort Collins, Co, USA). None of the dogs had evidence of metastasis at time of treatment. The median dose of cisplatin was 52.1 mg/m(2) (mean 55.4 mg/m(2), range 18.5-108.6 mg/m(2)). Wound complications were noted in 16 dogs (84.2%). Median follow-up time was 874 days (mean 777 days, range 125-1463 days). Nine dogs (47.3%) were alive at the time of analysis. Local recurrence occurred in three dogs (16.6%). The time to recurrence was 214, 264 and 874 days.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19453366/