Peer-reviewed veterinary case report
Cat with brain mass causing weakness and unsteady walk
By Ricci, Emanuele et al.·Published in The Journal of veterinary medical science·2010·Department of Animal Pathology, Italy·View original on PubMed →
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Original publication title: Intracranial cholesterol granuloma in a cat.
- Species:
- cat
Plain-English summary
A 4-year-old neutered male European cat was brought in because he had been getting weaker, uncoordinated, and depressed for the past five months. Tests showed he had slightly high cholesterol, and an MRI revealed a large mass in his brain. Unfortunately, after he passed away, a post-mortem exam confirmed the mass was a cholesterol granuloma, which is a type of growth caused by cholesterol deposits in the brain. Sadly, there was no treatment that could save him, as the mass had caused significant damage to his brain.
People also search for: cat weakness and ataxia · cat brain tumor symptoms · cholesterol granuloma in cats
Abstract
A case of intracranial cholesterol granuloma is described in a 4-year-old neutered European male cat presented with a 5-month history of progressive weakness, ataxia and depression. On clinical evaluation, haematological and biochemical profiles revealed only mild hypercholesterolemia and magnetic resonance imaging showed a large space-occupying extra-axial mass in the area of the falx, not homogeneous after contrast enhancement. At post-mortem examination, an orange-yellowish mass of 22 mm in diameter extended from the right frontal lobe to the temporo-parietal region, causing atrophy of the prosencephalic region of the brain. The site of origin of the mass was within the subarachnoid space of the supracallosum sulcus of the right cerebral hemisphere. Histological examination of the lesion revealed abundant deposits of cholesterol clefts, surrounded by clusters of macrophages and multinucleated giant cells. Neither inflammatory lesions, nor cholesterol deposits were detected in other areas of the brain and in other organs. On the basis of the histological examination, a diagnosis of intracranial cholesterol granuloma was made.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20543528/