Peer-reviewed veterinary case report
Intracranial bleeding in a 12-week-old Dobermann puppy with von
By Dunn, K J et al.·Published in The Veterinary record·1995·Department of Clinical Veterinary Medicine, United Kingdom·View original on PubMed →
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Original publication title: Intracranial haemorrhage in a dobermann puppy with von Willebrand's disease.
- Species:
- dog
Plain-English summary
A 12-week-old Doberman puppy was brought in because it was lethargic and having trouble walking. The vet found that the puppy had a low platelet count and signs of bleeding in the brain, which was linked to a condition called von Willebrand's disease that affects blood clotting. Despite treatment, the puppy did not improve and was sadly euthanized. A post-mortem examination showed severe bleeding in the brain, which was likely caused by the low levels of von Willebrand's factor and the low platelet count.
People also search for: Doberman puppy lethargy · von Willebrand's disease in dogs · puppy brain bleeding treatment
Abstract
Neurological examination of a lethargic, ataxic 12-week-old dobermann revealed decreased conscious proprioception in all its limbs. Haematological examination revealed a low platelet count. Cytological examination of a sample of cerebrospinal fluid revealed evidence of haemorrhage and chronic inflammation. The levels of von Willebrand's factor antigen were extremely low. Skull radiographs were consistent with mild hydrocephalus. Treatment resulted in little clinical improvement and the animal was euthanased. Post mortem examination of the brain revealed an internal hydrocephalus with haemorrhage into the ventricles. It was considered that the animal had suffered severe intracranial haemorrhage as a result of its low level of von Willebrand's factor antigen and that the bleeding may have been potentiated by the low platelet count.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/7571271/