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Peer-reviewed veterinary case report

Cat with spinal granular cell tumor causing paralysis and bladder

By Valentini, A et al.·Published in The Journal of small animal practice·2020·Department of Animal Medicine, Italy·View original on PubMed

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Original publication title: Intradural extramedullary granular cell tumour in a cat.

Species:
cat

Plain-English summary

A 7-year-old domestic shorthair cat was brought to the vet because it was having trouble walking, couldn't jump, had a paralyzed tail, and was unable to urinate. The vet found signs of a spinal issue and an MRI revealed a tumor in the spine. Unfortunately, the cat was diagnosed with a granular cell tumor, which is a rare type of tumor in cats. This case highlights the importance of early diagnosis for spinal tumors, but specific treatment outcomes were not detailed in the report.

People also search for: cat unable to walk · cat spinal tumor symptoms · cat bladder problems treatment

Abstract

A 7-year-old domestic shorthair cat was evaluated for progressive paraparesis, inability to jump, a paralysed tail and inability to void the bladder. Neurologic examination was consistent with a L4-S3 localisation. Survey radiographs of the lumbar vertebral column revealed L4-L7 vertebral body remodelling. A pre-contrast T1-weighted hyperintense, diffusely enhancing intradural lesion extending from L4 to S1 vertebral bodies was detected by MRI. Large, mesenchymal, round-to-polygonal cells arranged in nests or sheets were found on histologic examination at post mortem. These cells were characterised by abundant intracytoplasmic PAS-positive, diastase-resistant granules and positive immunoexpression of vimentin, S-100, neuron-specific enolase and desmin. This is the first report of a spinal granular cell tumour in a cat.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29745421/