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Peer-reviewed veterinary case report

Cat with stubborn skin infection on nose treated with amphotericin B

By Gremião, Isabella D F et al.·Published in Journal of feline medicine and surgery·2009·Evandro Chagas Clinical Research Institute/Oswaldo Cruz Foundation (Fiocruz), Brazil·View original on PubMed

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Original publication title: Intralesional amphotericin B in a cat with refractory localised sporotrichosis.

Species:
cat

Plain-English summary

A 3-year-old male crossbred cat was brought in for a stubborn skin lump on the bridge of his nose that didn’t go away after 9 months of oral medication for sporotrichosis, a fungal infection. To tackle this remaining lesion, the veterinarian added a treatment called intralesional amphotericin B, which involved injecting the medication directly into the lump. After three weekly injections alongside the oral medication, the lump completely disappeared. The cat has been healthy and free of any signs of the infection for over a year since finishing treatment.

People also search for: cat skin lump treatment · sporotrichosis in cats · amphotericin B for cat infection

Abstract

The present report concerns a case of sporotrichosis in a 3-year-old male crossbred cat. After 9 months of oral itraconazole (20mg/kg) therapy, all skin lesions had resolved with the exception of a single nodular lesion located on the bridge of the nose. Therefore, a combined therapy that included intralesional (IL) amphotericin B (1mg/kg) was started. The lesion resolved completely after three weekly administrations of IL amphotericin B, given in concert with oral itraconazole. The cat remains well 1 year after discontinuing therapy, with no signs of recurrence.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19553150/