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Peer-reviewed veterinary case report

Intramuscular mast cell tumors found and treated in 7 dogs

By Robinson, William P et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2017·University of Bristol, United Kingdom·View original on PubMed

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Original publication title: Intramuscular mast cell tumors in 7 dogs.

Species:
dog

Plain-English summary

A group of seven dogs with intramuscular mast cell tumors (a type of skin cancer) were treated after being diagnosed through fine-needle aspiration and imaging tests. Most of the dogs had surgery to remove the tumors, and six of them were still alive at least seven months later. Three of those dogs also received additional chemotherapy because their tumors showed aggressive features. Unfortunately, one dog that had chemotherapy due to the tumor's size and activity passed away shortly after treatment. Overall, the outlook for dogs with these tumors seems to be positive in most cases.

People also search for: dog mast cell tumor treatment · intramuscular tumor in dogs · dog cancer surgery recovery

Abstract

Mast cell tumors (MCTs) are commonly encountered in dogs and have been reported in cutaneous, conjunctival, oral mucosal, and gastrointestinal locations, but not in an intramuscular location. Medical records at 2 referral centers in the UK were examined to find cases of MCTs in this location. Seven dogs were identified as having an intramuscular MCT by a combination of fine-needle aspirate cytology and computed tomography or ultrasound. None of the dogs had evidence of local lymph node metastasis. Six dogs had no evidence of distant metastasis and surgery was carried out as the primary treatment option. Three of those dogs also had adjunctive chemotherapy due to a high Ki67 value or high mitotic index. All 6 dogs that had had surgery were alive at follow-up with a minimum elapsed time of 7 months. One dog had a course of chemotherapy due to the location, size, and evidence of biological activity of the tumor and died 23 days afterwards. The prognosis of intramuscular mast cell tumors appears to be favorable in most cases.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28878416/