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Peer-reviewed veterinary case report

Nasal discharge in two cats cured by clotrimazole infusion

By Furrow, Eva & Groman, Reid P·Published in Journal of the American Veterinary Medical Association·2009·Department of Clinical Studies, United States·View original on PubMed

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Original publication title: Intranasal infusion of clotrimazole for the treatment of nasal aspergillosis in two cats.

Species:
cat

Plain-English summary

Two cats, aged 13 and 11, were brought to the vet for nasal discharge that had lasted 4 days and 5 months, respectively. Tests showed they had a fungal infection in their noses caused by Aspergillus, which can lead to serious issues. Both cats underwent a procedure where a medication called clotrimazole was infused directly into their noses while they were under anesthesia. Thankfully, they both recovered well and showed complete resolution of their symptoms after the treatment.

People also search for: cat nasal discharge treatment · clotrimazole for cat fungal infection · nasal aspergillosis in cats

Abstract

CASE DESCRIPTION: 2 cats (13 and 11 years old) were evaluated to determine the cause of nasal discharge of varying duration (4 days and 5 months, respectively). CLINICAL FINDINGS: Computed tomography revealed marked turbinate destruction and soft tissue densities in the nasal passages. Histologic examination of nasal specimens revealed chronic active inflammation and branching fungal hyphae consistent with Aspergillus spp. Fungal culture of nasal specimens resulted in growth of Aspergillus spp. Testing yielded negative results for antibodies against Aspergillus spp. TREATMENT AND OUTCOME: Both cats were anesthetized and treated with a 1-hour intranasal infusion of clotrimazole. Recovery from the procedure was uncomplicated, and both cats had complete resolution of clinical signs. CLINICAL RELEVANCE: Little information is available on the treatment of nasal aspergillosis in cats, and the prognosis for affected animals is considered poor. The procedure for local intranasal infusion of clotrimazole in 2 cats was described here. Results and follow-up monitoring for both cats suggested that this may be a safe, effective, and durable treatment for cats with nasal aspergillosis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19912040/