Peer-reviewed veterinary case report
Intraocular nerve sheath tumor found in 9-year-old Shetland sheepdog
By Sato, Tsuneo et al.·Published in Veterinary ophthalmology·2005·College of Bioresource Sciences, Japan·View original on PubMed →
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Original publication title: Intraocular peripheral nerve sheath tumor in a dog.
- Species:
- dog
Plain-English summary
A 9-year-old Shetland sheepdog was diagnosed with a tumor inside its right eye. The tumor was made up of specific types of cells and was identified as a peripheral nerve sheath tumor (PNST), which is quite rare in dogs. This case is notable because it's the first time such a tumor has been reported in a dog's eye. Unfortunately, the abstract does not provide information on treatment or outcome, so it's unclear how the dog fared after diagnosis.
People also search for: dog eye tumor treatment · Shetland sheepdog eye problems · peripheral nerve sheath tumor in dogs
Abstract
A tumor within the right globe in a 9-year-old Shetland sheepdog was examined pathologically. The tumor was composed of spindle or oval cells arranged in interwoven bundles with intervening collagenous or mucinous matrices. Immunohistochemically, the tumor bound antibody directed to S-100 protein and vimentin, but not to desmin, actin smooth muscle, or neurofilament. Electron microscopy revealed that the tumor cells had poorly developed cytoplasmic processes, desmosomes between closely contiguous cells, and a discontinuous basement membrane-like material. Based on these findings, the tumor was diagnosed as a peripheral nerve sheath tumor (PNST) histologically. To the authors' knowledge, this is the first reported case of intraocular PNST in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16008710/