Peer-reviewed veterinary case report
Treatment of canine intranasal carcinoma with surgery and special
By Maruo, Takuya et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2019·Veterinary Teaching Hospital (Maruo, United States·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Intraoperative acridine orange photodynamic therapy and cribriform electron-beam irradiation for canine intranasal carcinomas: 14 cases.
- Species:
- dog
Plain-English summary
A group of dogs with intranasal tumors, which are often cancerous, underwent surgery followed by a special light therapy and radiation treatment to help control the cancer. Out of 14 dogs treated, most had early-stage tumors, but some had more advanced stages. Unfortunately, about half of the dogs experienced tumor regrowth within six months, but the overall survival time after treatment was around 22 months. The treatments had only mild side effects. This approach may help manage these difficult-to-treat tumors better than surgery alone.
People also search for: dog nasal cancer treatment · canine intranasal tumor survival rate · photodynamic therapy for dogs
Abstract
Canine intranasal carcinomas are almost always malignant. Surgery alone often results in rapid tumor regrowth. Radiotherapy is the treatment of choice for dogs with intranasal tumors. Here, we retrospectively assessed treatment of intranasal carcinoma by marginal tumor resection followed by intraoperative acridine orange (AO) photodynamic therapy (PDT) and cribriform plate electron-beam intraoperative radiotherapy (IORT). Fourteen canine cases were assessed, 12 of which had stage I tumors, one with stage III, and one with stage IV. Recurrence was detected in 8, with a median recurrence from the time of treatment of 6 months (range: 3 to 16 months). The median progression-free survival time and overall survival time after treatment were 13 and 22 months, respectively. Adverse events were mild. Marginal tumor resection followed by intraoperative AO-PDT and cribriform plate electron-beam IORT may increase the tumor control time in dogs with marginally resectable intranasal malignant tumors beyond that incurred by surgery alone.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31080264/