Peer-reviewed veterinary case report
Glycosaminoglycan bladder treatment may reduce repeat urethral
By Bradley, Allison M & Lappin, Michael R·Published in Journal of feline medicine and surgery·2014·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Intravesical glycosaminoglycans for obstructive feline idiopathic cystitis: a pilot study.
- Species:
- cat
Plain-English summary
A group of cats with a painful condition called idiopathic cystitis, which can cause dangerous urethral blockages, was treated with a special product containing glycosaminoglycans infused directly into their bladders. In a study, none of the nine cats receiving this treatment experienced further blockages within a week, while three out of seven cats that received a placebo did have repeated obstructions. This suggests that the glycosaminoglycan treatment might help prevent these serious issues, and further research is encouraged to confirm its effectiveness.
People also search for: cat urethral obstruction treatment · feline idiopathic cystitis management · glycosaminoglycans for cats
Abstract
Feline idiopathic cystitis is a common condition, often resulting in repeated episodes of life-threatening urethral obstruction. Defective urinary bladder glycosaminoglycans have been implicated as a causal factor. In this report, a commercially available glycosaminoglycan product was infused into the urinary bladders of cats with urethral obstruction from idiopathic cystitis to study the effect on repeated obstruction. In this randomized, blind, placebo-controlled clinical trial, the therapeutic protocol was well tolerated with no adverse effects. Whereas no glycosaminoglycan-treated cats (n = 9) developed repeated urethral obstruction during the 7 day follow-up period, 3/7 placebo-treated cats developed repeated obstructions. Approaching statistical significance (P = 0.06), these data suggest that further investigation of this new treatment option is warranted.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24196569/