Peer-reviewed veterinary case report
Invasive mesothelioma tumor in 11-year-old Golden Retriever dog
By Reggeti, F et al.·Published in Veterinary pathology·2005·Department of Pathobiology, Canada·View original on PubMed →
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Original publication title: Invasive epithelial mesothelioma in a dog.
- Species:
- dog
Plain-English summary
An 11-year-old neutered male Golden Retriever was diagnosed with an invasive epithelial mesothelioma, a type of cancer affecting the membranes around the heart and lungs. The tumor spread to various areas, including the pericardium and pleura, and was found in the dog's thoracic fluid, indicating a serious condition. The cancerous cells showed aggressive characteristics, which helped veterinarians identify it as mesothelioma rather than other types of tumors. Unfortunately, this type of cancer is often difficult to treat effectively, and the prognosis can be poor.
People also search for: dog cancer symptoms · Golden Retriever tumor treatment · mesothelioma in dogs
Abstract
This report describes the gross, microscopic, and immunohistochemical features of an invasive epithelial mesothelioma in an 11-year-old neutered male Golden Retriever. The tumor involved the pericardium, pleura, mediastinum, and peritoneum and invaded into submesothelial tissues. Neoplastic cells in the thoracic fluid showed prominent features of malignancy in a background of mixed inflammatory cells and scattered erythrocytes. Histologically, the tumor consisted of nests of epithelioid cells with frequent mitotic figures and multinucleation that infiltrated submesothelial tissues. Neoplastic cells strongly coexpressed vimentin and cytokeratin intermediate filaments, which assisted in the differentiation from other epithelial tumors of nonmesothelial origin.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15657276/