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Peer-reviewed veterinary case report

Cat with fungal nasal infection from Metarhizium anisopliae

By Muir, D et al.·Published in Medical mycology·1998·Royal North Shore Hospital·View original on PubMed

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Original publication title: Invasive hyphomycotic rhinitis in a cat due to Metarhizium anisopliae.

Species:
cat

Plain-English summary

A cat with a 4-month history of noisy breathing, nasal discharge, and swelling on the nose was diagnosed with a fungal infection called invasive mycotic rhinitis. Tests showed the presence of a specific fungus, Metarhizium anisopliae, in the nasal area. The cat was treated with an antifungal medication called itraconazole, which helped address the infection. This case is notable as it is the first documented instance of this particular fungus affecting a mammal.

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Abstract

Invasive mycotic rhinitis was diagnosed in a cat with a 4-month history of stertor, nasal discharge and subcutaneous swelling of the nasal bridge. Histology demonstrated fungal hyphae in representative biopsies of the nasal cavity and subcutaneous mass. Mycological culture demonstrated a pure growth of Metarhizium anisopliae var. anisopliae. The infection was treated with orally administered itraconazole. This is the first well documented case of infection by M. anisopliae in a mammalian host.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9776813/