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Peer-reviewed veterinary case report

Golden Retriever with tendon sheath cancer causing bone loss in leg

By Coleman, Mary et al.·Published in Journal of the American Animal Hospital Association·2021·View original on PubMed

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Original publication title: Invasive Tendon Sheath Fibrosarcoma Causing Radial Osteolysis in a Golden Retriever.

Species:
dog

Plain-English summary

A 7-year-old Golden Retriever was brought in for limping on the left front leg, and X-rays showed a bone lesion in the radius along with swelling. A needle test suggested a type of cancer called sarcoma, but after the leg was amputated, further tests revealed it was a rare fibrosarcoma that started in the tendon sheath. Fortunately, about 17 months after the surgery, the dog is doing well and has shown no signs of cancer returning.

People also search for: golden retriever limping · dog leg cancer treatment · fibrosarcoma in dogs · dog amputation recovery

Abstract

This case report details a previously undescribed malignancy of the tendon sheath in a golden retriever. This dog originally presented with lameness of the left forelimb, at which point radiographs revealed a monostotic, lytic lesion of the distal radius with overlying soft-tissue swelling. A fine-needle aspirate was performed, and cytology was compatible with a sarcoma, with the primary differential being an osteosarcoma. After amputation, the leg was submitted for histopathology, which revealed inconsistencies with a typical osteosarcoma lesion, including lack of osteoid deposition. Second opinion histopathology showed a fibrosarcoma that appeared to have originated in the tendon sheath of an extensor tendon and then secondarily invaded the radius. At the time of publication, ∼17 mo after amputation, the dog continues to do well without any evidence of recurrent or metastatic disease.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34606584/