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Peer-reviewed veterinary case report

Cat with painful bladder found to have inverted urothelial papilloma

By Brunetti, Barbara et al.·Published in Veterinary pathology·2022·University of Bologna, Italy·View original on PubMed

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Original publication title: Inverted urothelial papilloma in a cat.

Species:
cat

Plain-English summary

A 12-year-old female cat was brought to the vet with signs of lower urinary tract issues, including a painful bladder. During an examination, the vet found a growth in the bladder that was removed through surgery. The biopsy results showed it was an inverted urothelial papilloma, a type of benign tumor. One year later, the cat was doing well, with no urinary problems and a normal bladder on ultrasound.

People also search for: cat urinary problems · cat bladder tumor treatment · signs of bladder issues in cats

Abstract

A 12-year-old neutered female cat was referred with clinical signs referable to lower urinary tract disease. Clinical examination revealed a tense, painful urinary bladder, and proximal urethral thickening. Endoscopic studies showed a pedunculated mass with polypoid projections. Multiple full-thickness mucosal biopsies were obtained, and the mass was almost completely excised. The neoplasm was confined to the mucosa and consisted of epithelial cells arranged in anastomosing trabeculae and nests, growing downward into the lamina propria. Neoplastic cells showed minimal atypia and low mitotic activity. Histological findings were consistent with inverted urothelial papilloma. Feline papillomavirus DNA was not amplified from biopsies. One year later, the cat had no urological signs, and urinary bladder was normal at ultrasound. To the authors' knowledge, this is the first report of a case of inverted urothelial papilloma in a cat and is a differential diagnosis for low-grade urothelial carcinoma and other lesions with inverted growth pattern.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34669543/