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Peer-reviewed veterinary case report

High triglycerides found in healthy Miniature Schnauzers

By Xenoulis, Panagiotis G et al.·Published in Journal of veterinary internal medicine·2007·Department of Small Animal Clinical Sciences, United States·View original on PubMed

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Original publication title: Investigation of hypertriglyceridemia in healthy Miniature Schnauzers.

Species:
dog

Plain-English summary

A group of 192 healthy Miniature Schnauzers were tested for high triglyceride levels, a condition known as hypertriglyceridemia. It was found that about one-third of these dogs had triglyceride levels above the normal range, which is significantly higher compared to other breeds. The study also revealed that as these dogs aged, their triglyceride levels tended to increase. This suggests that Miniature Schnauzers may be more prone to this condition, especially as they get older. Pet owners should monitor their Schnauzers' triglyceride levels, particularly in older dogs, and consult their veterinarian if they have concerns.

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Abstract

BACKGROUND: Idiopathic hypertriglyceridemia has been reported in Miniature Schnauzers (MS). However, studies investigating the prevalence of this disorder in a large population of MS are lacking. HYPOTHESIS: Hypertriglyceridemia is prevalent in healthy MS. ANIMALS: This study used 192 healthy MS and 38 healthy dogs of other breeds (control dogs). METHODS: Serum triglyceride and cholesterol concentrations were measured and statistically compared in both the MS and control group. Dogs were categorized based on their age, and median serum triglyceride concentrations were compared among different age groups. RESULTS: A total of 63 (32.8%) of the 192 MS had serum triglyceride concentrations above the reference range. In contrast, of the 38 control dogs, only 2 (5.3%) had serum triglyceride concentrations above the reference range. The median serum triglyceride concentration in MS was 73.5 mg/dL, which was significantly higher as compared to that of the control group (median, 55 mg/dL; P = .0005). Serum cholesterol concentration was above the reference range in 9 (9.0%) of 100 MS and in 2 (5.3%) of the control dogs. Mean serum cholesterol concentrations were not significantly different between the 2 groups (P = .1374). Median serum triglyceride concentrations in MS increased significantly with age (P < .0001), and there was a significant positive correlation between serum triglyceride concentrations and age (Spearman r = 0.47; P < .0001). There was no difference in serum triglyceride concentrations between male and female MS (P = .48). CONCLUSION: Healthy MS have a high prevalence of hypertriglyceridemia as compared to healthy dogs of other breeds. Both the prevalence and severity of hypertriglyceridemia increase with age.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18196730/