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Peer-reviewed veterinary case report

Subclinical urinary infection in cats on long-term steroids

By Lockwood, Samantha L et al.·Published in Veterinary dermatology·2018·Dermatology for Animals, United States·View original on PubMed

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Original publication title: Investigation of subclinical bacteriuria in cats with dermatological disease receiving long-term glucocorticoids and/or ciclosporin.

Species:
cat

Plain-English summary

A group of 32 cats receiving long-term treatment with glucocorticoids (steroids) and/or ciclosporin (an immunosuppressant) for various health issues were tested for bladder infections. The tests showed that none of these cats had a positive urine culture, meaning they did not have a bacterial infection in their urine. In comparison, only one out of 34 healthy cats had a positive culture. This suggests that long-term use of these medications does not increase the risk of bladder infections in cats.

People also search for: cat bladder infection symptoms · glucocorticoids side effects in cats · ciclosporin for cat skin problems

Abstract

BACKGROUND: Dogs receiving long-term glucocorticoids or ciclosporin have an increased frequency of bacteriuria. No studies have investigated the frequency of bacteriuria in cats receiving long-term glucocorticoids and/or ciclosporin. HYPOTHESES/OBJECTIVES: To document whether subclinical bacteriuria occurs in cats receiving long-term glucocorticoid and/or ciclosporin for management of chronic disease. ANIMALS: Thirty two cats treated with parenteral glucocorticoids and/or oral glucocorticoids and/or ciclosporin were included. METHODS: Thirty two cats receiving oral glucocorticoids and/or ciclosporin for at least three months or at least two injections of long-acting glucocorticoids within the preceding six months were evaluated. Thirty four healthy cats were used as a control group. Urinalysis and urine culture was performed on urine samples collected by cystocentesis from each cat. RESULTS: In the glucocorticoid/ciclosporin group, none of 32 cats had a positive urine culture. In the control group, one of 34 cats had a positive urine culture. There were no statistically significant differences between the urinalyses from either group. CONCLUSIONS AND CLINICAL IMPORTANCE: There was no evidence to suggest that administration of long-term glucocorticoids and/or ciclosporin is associated with bacteriuria in cats.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28833821/