Peer-reviewed veterinary case report
Oxidative stress markers in dogs infected with Babesia vogeli
By Ciftci, Gulay et al.·Published in Veterinary parasitology·2014·Department of Biochemistry·View original on PubMed →
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Original publication title: Investigation of the 8-hydroxy-2'-deoxyguanosine, total antioxidant and nitric oxide levels of serum in dogs infected with Babesia vogeli.
- Species:
- dog
Plain-English summary
A group of dogs infected with Babesia vogeli, a parasite that can cause serious health issues, showed signs of oxidative stress, which is an imbalance in the body that can lead to cell damage. Blood tests revealed higher levels of a specific marker (8-OHdG) associated with oxidative stress in these infected dogs compared to healthy ones. Additionally, levels of nitric oxide were elevated, while total antioxidant capacity decreased, indicating a struggle in the dogs' bodies to fight off the effects of the infection. Understanding these changes can help veterinarians better assess and treat dogs suffering from Babesia infections.
People also search for: dog Babesia infection symptoms · oxidative stress in dogs · treatment for Babesia vogeli in dogs
Abstract
Oxidative stress was defined as corruption of balance between oxidant-antioxidant states in favor of oxidants. In this study, it was aimed to determine oxidative stress in naturally infected dogs with Babesia vogeli. The 8-hydroxy-2'-deoxyguanosine (8-OHdG), nitric oxide (NO) and total antioxidant capacity (TAC) levels in the sera were analyzed by ELISA. 8-OHdG levels increased in B. vogeli infected dogs compared to control group (P<0.05). Also, NO levels increased while TOC levels decreased in B. vogeli infected dogs but these variations were not found as statistically important (P>0.05).
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24882747/