Peer-reviewed veterinary case report
Exercise testing effects on heart in healthy Boxer dogs
By Agarwal, Deepmala et al.·Published in Journal of veterinary internal medicine·2023·Department of Companion Animals, Canada·View original on PubMed →
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Original publication title: Investigation of the cardiac effects of exercise testing on apparently healthy Boxer dogs.
- Species:
- dog
Plain-English summary
A group of 30 healthy Boxer dogs underwent exercise testing to see how it affected their heart health. During the test, which involved brisk stair climbing for less than five minutes, some dogs showed an increase in abnormal heartbeats called premature ventricular complexes (PVCs) and higher levels of a heart protein called troponin-I. Specifically, 11 dogs had more than 100 PVCs in a day, and those with a genetic mutation called striatin had even more PVCs and higher troponin-I levels after exercise. This suggests that exercise testing could help identify heart issues in Boxers that might not be obvious at rest.
People also search for: Boxer dog heart problems · exercise testing for Boxer dogs · premature ventricular complexes in dogs
Abstract
BACKGROUND: Holter electrocardiographic monitoring is a cornerstone of diagnostic testing for arrhythmogenic cardiomyopathy (ACM) in Boxer dogs, but physical activity during monitoring is not controlled. In humans, exercise testing (ExT) can identify latent tachyarrhythmias associated with cardiomyopathy, and exercise increases serum cardiac troponin-I concentrations ([hs-cTnI]). These effects have not yet been investigated in Boxer dogs. HYPOTHESIS/OBJECTIVES: Subjecting Boxer dogs to brief, moderate-intensity ExT can identify changes in Holter recordings and [hs-cTnI] compared to baseline results. ANIMALS: Thirty overtly healthy, client-owned Boxer dogs. METHODS: Prospective interventional study. Dogs underwent baseline diagnostic testing including 24-hour Holter monitoring and [hs-cTnI], followed by brief ExT (accompanied, brisk stair-climbing and -descending for <5 minutes). RESULTS: Eleven dogs (37%) had >100 premature ventricular complexes (PVCs)/24 hours at baseline (3), ExT (3), or both (5). After ExT, these dogs had more PVCs/24 hours and greater increases in [hs-cTnI] compared to those with ≤100 PVCs/24 hours. Dogs with the striatin mutation had more PVCs/24 hours and a greater increase in [hs-cTnI] after ExT than did dogs without the striatin mutation. CONCLUSIONS AND CLINICAL IMPORTANCE: Exercise testing may improve the binary classification of Boxer dogs with or without ACM by increasing the number of PVCs and [hs-cTnI] in affected dogs to a greater degree than in unaffected dogs. This effect also is associated with presence or absence of the striatin mutation. Exercise should be a controlled variable when screening Boxer dogs for ACM.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37578273/