Peer-reviewed veterinary case report
Preventing newborn puppy hookworm with topical imidacloprid
By Krämer, F et al.·Published in Zoonoses and public health·2009·Institute for Parasitology, Germany·View original on PubMed →
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Original publication title: Investigations into the prevention of neonatal Ancylostoma caninum infections in puppies by application of imidacloprid 10% plus moxidectin 2.5% topical solution to the pregnant dog.
- Species:
- dog
Plain-English summary
Three pregnant beagle dogs infected with hookworms were treated with a topical solution containing imidacloprid and moxidectin to see if it could prevent infections in their puppies. The treated dogs had healthy litters, with no signs of hookworm infection in the puppies, while two of the untreated dogs had puppies that were infected after giving birth. The treatment was effective, and no side effects were noted in either the mothers or their puppies. This suggests that using this topical treatment on pregnant dogs can help protect newborn puppies from hookworm infections.
People also search for: puppy hookworm prevention · pregnant dog treatment for parasites · beagle puppy health care
Abstract
The aim of the investigation was to examine whether a single topical administration of a combination of imidacloprid and moxidectin to pregnant dogs could prevent neonatal infections with reactivated Ancylostoma caninum larvae. Three pregnant beagles, infected with A. caninum, were treated topically with the combination on day 56 of pregnancy. Three further dogs served as untreated controls. Treatment appeared to prevent neonatal infections in the puppies completely. Neither intestinal stages nor somatic larvae were found in two examined puppies per litter. All puppies and dams of the treatment group remained coproscopically negative. No side-effects in dams or puppies were observed. Two of three untreated dams showed a patent infection after parturition. Necropsy of two puppies of each negative control litter revealed seven intestinal and five somatic A. caninum stages in total. One litter of the untreated dams showed a patent infection 33 days after parturition. In the other two litters, no representative sample sizes could be collected.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18793274/