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Peer-reviewed veterinary case report

Radiation treatment added after surgery for dog skin mast cell tumors

By Northrup, Nicole C et al.·Published in Journal of the American Animal Hospital Association·2004·Department of Small Animal Medicine and Surgery, United States·View original on PubMed

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Original publication title: Iridium-192 interstitial brachytherapy as adjunctive treatment for canine cutaneous mast cell tumors.

Species:
dog

Plain-English summary

Eleven dogs with skin tumors called mast cell tumors were treated with surgery followed by a special type of radiation therapy using iridium-192. The tumors were either grade II or III, which indicates their severity. After treatment, six of the dogs did not have any recurrence of their tumors for an average of about 942 days, while five dogs did experience a recurrence after about 1391 days. Most dogs handled the side effects well, and any long-term effects were mild. One dog did develop a different type of tumor in the area where it received radiation.

People also search for: dog skin tumor treatment · mast cell tumor in dogs · radiation therapy for dog tumors

Abstract

Eleven dogs with cutaneous mast cell tumors (MCTs) were treated with surgery and iridium-192 ((192)Ir) interstitial brachytherapy. Minimum tumor doses ranged from 47.2 to 63.3 Gy. Treated tumors were classified as grade II (n=7) or III (n=4). Five dogs had recurrences with a median progression-free interval of 1391 days, and six dogs had no recurrence at a median follow-up time of 942 days. Acute adverse effects were well tolerated, and late effects were mild. One dog developed a second tumor of a different cell type in the radiation treatment field.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15238561/