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Peer-reviewed veterinary case report

Iridium-192 interstitial brachytherapy as adjunctive treatment for canine cutaneous mast cell tumors.

Journal:
Journal of the American Animal Hospital Association
Year:
2004
Authors:
Northrup, Nicole C et al.
Affiliation:
Department of Small Animal Medicine and Surgery · United States
Species:
dog

Abstract

Eleven dogs with cutaneous mast cell tumors (MCTs) were treated with surgery and iridium-192 ((192)Ir) interstitial brachytherapy. Minimum tumor doses ranged from 47.2 to 63.3 Gy. Treated tumors were classified as grade II (n=7) or III (n=4). Five dogs had recurrences with a median progression-free interval of 1391 days, and six dogs had no recurrence at a median follow-up time of 942 days. Acute adverse effects were well tolerated, and late effects were mild. One dog developed a second tumor of a different cell type in the radiation treatment field.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15238561/