Peer-reviewed veterinary case report
Dog with iridociliary eye tumor showing ballooning cells
By Morioka, Yui et al.·Published in The Journal of veterinary medical science·2025·MLT Co., Japan·View original on PubMed →
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Original publication title: Iridociliary adenoma with ballooning change in a dog.
- Species:
- dog
Plain-English summary
A 13-year-old male beagle was found to have an unusual mass in his right eye. The veterinarian decided to remove the entire eyeball to treat the issue. After examining the mass, it was determined to be a benign growth called an iridociliary adenoma, which means it wasn't cancerous and hadn't spread. The dog recovered well after surgery, and there were no signs of invasive growth.
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Abstract
An ocular mass was noted in the right iridociliary region of a 13-year-old male beagle dog. The right eyeball was surgically removed. Histopathologically, the mass was located mainly in the ciliary body and appeared to be continuous with non-pigmented epithelial cells. The polygonal neoplastic cells proliferated in sheets with periodic acid-Schiff-positive basement membrane material. Neoplastic cells had small round nuclei with no atypia or mitosis, and abundant, pale eosinophilic, granular, and rarified cytoplasm displayed ballooning change. No invasive growth or metastasis was observed. Immunohistochemically, the cells were positive for vimentin, neuron-specific enolase, and S100, and negative for cytokeratin AE1/AE3, Iba-1, CD204, MelanA, Sox10, and PNL2. Based on these findings, the lesion was diagnosed as an iridociliary adenoma with ballooning change.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39631874/