Peer-reviewed veterinary case report
Do you need to wait between different eye drops for dogs?
By Arad, Dikla et al.·Published in Veterinary ophthalmology·2021·Koret School of Veterinary Medicine·View original on PubMed →
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Original publication title: Is it necessary to wait several minutes between applications of different topical ophthalmic solutions? A preliminary study with tropicamide eye drops in healthy dogs.
- Species:
- dog
Plain-English summary
A group of healthy Labrador and golden retriever dogs were tested to see how long to wait between applying different eye drops. The study focused on tropicamide eye drops, which help widen the pupils, and found that waiting just one minute before or after applying a saline drop was enough to achieve the best results. The dogs reached their maximum pupil size 30 minutes after receiving the tropicamide, and this effect lasted for about three hours. This suggests that pet owners can apply different eye drops with just a short wait in between for effective treatment.
People also search for: dog eye drops timing · tropicamide for dogs · how long to wait between eye drops for dogs
Abstract
OBJECTIVE: To evaluate the efficacy of topical tropicamide when placed at different time intervals before or after a saline drop. ANIMALS STUDIED: Eight healthy Labrador and golden retriever dogs. PROCEDURES: The effect of 1% tropicamide on pupillary diameter (PD) was measured over 240 min when administered alone (control) and then 1 and 5 min prior to, or following, application of a saline drop, with 1-week washout between each of the five trials. Data were analyzed using repeated-measures ANOVA and Tukey post hoc test. RESULTS: Only 6/110 pairwise comparisons among the 5 trials were statistically significant (p ≤ .035), with post-hoc analysis showing no significant differences (p ≥ .14) between the overall means of all trials. In all five trials, maximal PD was reached 30 min after tropicamide application and maintained until 210 min for 180 min (p = .0005). CONCLUSIONS: Our results suggest that waiting 1 min between applications of different ophthalmic solutions may be sufficient for maximal drug effect. Care should be taken when extrapolating these results to other species and different ophthalmic formulations.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34402570/