Peer-reviewed veterinary case report
Ischemia-reperfusion injury of the mouse kidney.
- Journal:
- Methods in molecular biology (Clifton, N.J.)
- Year:
- 2012
- Authors:
- Oxburgh, Leif & de Caestecker, Mark P
- Affiliation:
- Maine Medical Center Research Institute · United States
Abstract
Studies of the complex responses of the kidney to acute injury have yielded important insights into mechanisms of tissue injury and repair. A variety of injury models have contributed to this impressive body of knowledge, but the ischemia-reperfusion (IR) model has perhaps been the most widely used. This chapter contains a detailed method description for IR injury in the mouse together with notes on blood sampling and tissue harvesting. The aim of the chapter is to provide the novice with a step-by-step guide to establishing this procedure in their research program.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22639277/