Peer-reviewed veterinary case report
Isolation and Characterization of Madariaga Virus from a Horse in Paraíba State, Brazil.
- Journal:
- Transboundary and emerging diseases
- Year:
- 2017
- Authors:
- Silva, M L C R et al.
- Affiliation:
- Fundaç · Brazil
- Species:
- horse
Plain-English summary
Researchers studied a virus called Madariaga virus (MADV), which is a type of eastern equine encephalitis virus found in South America. They isolated this virus from a horse in Paraíba State, Brazil, and found that it is genetically different from similar viruses in North America. Their findings confirm that there are three different genetic groups of MADV, and the strain from Brazil is part of a group that is also related to viruses found in Peru, Colombia, and Venezuela. This research helps us understand the diversity and spread of this virus in South America.
Abstract
Madariaga virus (MADV), the new species designation for the South American isolates of eastern equine encephalitis virus (EEEV), is genetically divergent and substantially different in ecology and pathogenesis from North American EEEV strains. We isolated and characterized a MADV isolate obtained from a horse in Brazil. Our results support previous phylogenetic studies showing there are three genetically distinct MADV lineages. The MADV isolate from Paraíba State belongs to the South American lineage III and is closely related to Peruvian, Colombian and Venezuelan isolates.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/26608567/