Peer-reviewed veterinary case report
Isolation and molecular characterization of a urease-negative Actinobacillus pleuropneumoniae mutant.
- Journal:
- Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
- Year:
- 2018
- Authors:
- Ito, Hiroya et al.
- Affiliation:
- The National Institute of Animal Health · Japan
Abstract
An atypical urease-negative mutant of Actinobacillus pleuropneumoniae serovar 2 was isolated in Japan. Nucleotide sequence analysis of the urease gene cluster revealed that the insertion of a short DNA sequence into the cbiM gene was responsible for the urease-negative activity of the mutant. Veterinary diagnostic laboratories should be watchful for the presence of aberrant urease-negative A. pleuropneumoniae isolates.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/29145759/