Peer-reviewed veterinary case report
Isolation and molecular characterization of Brazilian turkey reovirus from immunosuppressed young poults.
- Journal:
- Archives of virology
- Year:
- 2014
- Authors:
- Rosa, Ana Carolina G et al.
- Affiliation:
- University of Sã · Brazil
- Species:
- bird
Abstract
In this study, we investigated turkey reovirus (TReoV) in tissue samples from young birds, aged 15 days. RT-PCR for TReoV detected 3.3 % positive samples and TReoV was successfully isolated in Vero cells. Histological analysis of positive bursa of Fabricius (BF) revealed atrophied follicles and lymphocyte depletion. The number of CD8+, CD4+ and IgM+ cells was lower in infected BF. Phylogenetic analysis based on S3 gene showed that the Brazilian TReoV isolates clustered in a single group with 98-100 % similarity to TReoV strains circulating in the United States. This is the first indication that TReoV infection may be a contributing factor to immunosuppression in young birds.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/24327096/