Peer-reviewed veterinary case report
It takes two to untangle: Combined stimulation of adult neurogenesis reverts AD symptoms.
- Journal:
- Cell stem cell
- Year:
- 2023
- Authors:
- Gabarró-Solanas, Rut & Urbán, Noelia
- Affiliation:
- Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA)
Abstract
Alzheimer's disease (AD) is associated with reduced adult hippocampal neurogenesis and impaired hippocampal-dependent behaviors. Li et al.report that stimulating adult neurogenesis combined with new-born neuron activation ameliorates behavioral symptoms and plaque deposition in AD mouse models. This supports boosting adult neurogenesis as a potential therapeutic approach for AD-related cognitive decline.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/37028395/